pathway	-log10(p-value)	genes
REACTOME_CELL_CYCLE	31.99	CDK1,PCNA,MCM8,CDC6,ORC6,RFC4,CDC20,MCM2,MCM4,MCM6,MCM7,E2F1,CDT1,CDC25A,UBE2C,CCNE1,DNA2,DBF4,CDC7,KIF2C,MAD2L1,BUB1B,CCNE2,KIF23,CDK4,CKS1B,CHEK1,CENPN,RRM2,PKMYT1,AURKB,BRCA1,TUBG1,CCNB2,LMNB1,CHEK2,BIRC5,BUB1,DSN1,SYNE1,MYBL2,CCND2,HJURP
REACTOME_CELL_CYCLE_MITOTIC	28.96	CDK1,PCNA,MCM8,CDC6,ORC6,RFC4,CDC20,MCM2,MCM4,MCM6,MCM7,E2F1,CDT1,CDC25A,UBE2C,CCNE1,DNA2,DBF4,CDC7,KIF2C,MAD2L1,BUB1B,CCNE2,KIF23,CDK4,CKS1B,CENPN,RRM2,PKMYT1,AURKB,TUBG1,CCNB2,BIRC5,BUB1,DSN1,MYBL2,CCND2
REACTOME_MITOTIC_G1_G1_S_PHASES	20.14	CDK1,PCNA,MCM8,CDC6,ORC6,MCM2,MCM4,MCM6,MCM7,E2F1,CDT1,CDC25A,CCNE1,DBF4,CDC7,CCNE2,CDK4,CKS1B,RRM2,PKMYT1,MYBL2,CCND2
REACTOME_CELL_CYCLE_CHECKPOINTS	19.66	CDK1,MCM8,CDC6,ORC6,RFC4,CDC20,MCM2,MCM4,MCM6,MCM7,CDC25A,UBE2C,CCNE1,DBF4,CDC7,MAD2L1,BUB1B,CCNE2,CHEK1,CCNB2,CHEK2
REACTOME_DNA_REPLICATION	19.65	PCNA,MCM8,CDC6,ORC6,RFC4,CDC20,MCM2,MCM4,MCM6,MCM7,E2F1,CDT1,DNA2,DBF4,CDC7,KIF2C,MAD2L1,BUB1B,KIF23,CENPN,AURKB,BIRC5,BUB1,DSN1
REACTOME_G2_M_CHECKPOINTS	17.96	CDK1,MCM8,CDC6,ORC6,RFC4,MCM2,MCM4,MCM6,MCM7,CDC25A,DBF4,CDC7,CHEK1,CCNB2,CHEK2
REACTOME_G1_S_TRANSITION	17.84	CDK1,PCNA,MCM8,CDC6,ORC6,MCM2,MCM4,MCM6,MCM7,E2F1,CDT1,CDC25A,CCNE1,DBF4,CDC7,CCNE2,CKS1B,RRM2,PKMYT1
REACTOME_MITOTIC_M_M_G1_PHASES	17.05	MCM8,CDC6,ORC6,CDC20,MCM2,MCM4,MCM6,MCM7,E2F1,CDT1,DBF4,CDC7,KIF2C,MAD2L1,BUB1B,KIF23,CENPN,AURKB,BIRC5,BUB1,DSN1
REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS	14.23	MCM8,CDC6,ORC6,RFC4,MCM2,MCM4,MCM6,MCM7,CDC25A,DBF4,CDC7,CHEK1
REACTOME_S_PHASE	14.22	PCNA,MCM8,CDC6,ORC6,RFC4,MCM2,MCM4,MCM6,MCM7,CDT1,CDC25A,CCNE1,DNA2,CCNE2,CDK4,CKS1B
REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX	12.03	MCM8,CDC6,ORC6,MCM2,MCM4,MCM6,MCM7,CDT1,DBF4,CDC7
REACTOME_E2F_MEDIATED_REGULATION_OF_DNA_REPLICATION	11.59	CDK1,PCNA,MCM8,CDC6,ORC6,E2F1,CDT1,CDC25A,CCNE1,RRM2
REACTOME_G1_S_SPECIFIC_TRANSCRIPTION	10.48	CDK1,PCNA,CDC6,E2F1,CDT1,CDC25A,CCNE1,RRM2
REACTOME_G0_AND_EARLY_G1	9.7	CDK1,PCNA,CDC6,E2F1,CDC25A,CCNE1,CCNE2,MYBL2
REACTOME_M_G1_TRANSITION	9.62	MCM8,CDC6,ORC6,MCM2,MCM4,MCM6,MCM7,E2F1,CDT1,DBF4,CDC7
REACTOME_DNA_STRAND_ELONGATION	9.17	PCNA,MCM8,RFC4,MCM2,MCM4,MCM6,MCM7,DNA2
REACTOME_SYNTHESIS_OF_DNA	9.08	PCNA,MCM8,CDC6,ORC6,RFC4,MCM2,MCM4,MCM6,MCM7,CDT1,DNA2
REACTOME_ASSEMBLY_OF_THE_PRE_REPLICATIVE_COMPLEX	8.04	MCM8,CDC6,ORC6,MCM2,MCM4,MCM6,MCM7,E2F1,CDT1
REACTOME_MITOTIC_PROMETAPHASE	7.04	CDC20,KIF2C,MAD2L1,BUB1B,CENPN,AURKB,BIRC5,BUB1,DSN1
REACTOME_KINESINS	6.86	KIF2C,KIF23,KIF4A,RACGAP1,KIF11,KIF15
REACTOME_UNWINDING_OF_DNA	6.86	MCM8,MCM2,MCM4,MCM6,MCM7
REACTOME_ORC1_REMOVAL_FROM_CHROMATIN	6.75	MCM8,CDC6,ORC6,MCM2,MCM4,MCM6,MCM7,CDT1
REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION	5.4	CDK1,MCM8,ORC6,CDC25A
REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX	5.27	MCM8,CDC6,ORC6,E2F1
REACTOME_CHROMOSOME_MAINTENANCE	4.94	PCNA,RFC4,DNA2,CENPN,BRCA1,LMNB1,SYNE1,HJURP
REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION	4.82	CDK1,CDC25A,PKMYT1,CCNB2
REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION	4.71	KIF2C,KIF23,KIF4A,RACGAP1,KIF11,KIF15,GATA6,EHD2
REACTOME_INHIBITION_OF_THE_PROTEOLYTIC_ACTIVITY_OF_APC_C_REQUIRED_FOR_THE_ONSET_OF_ANAPHASE_BY_MITOTIC_SPINDLE_CHECKPOINT_COMPONENTS	4.13	CDC20,UBE2C,MAD2L1,BUB1B
REACTOME_MITOTIC_G2_G2_M_PHASES	4.11	CDK1,E2F1,CDC25A,PKMYT1,TUBG1,CCNB2
REACTOME_REGULATION_OF_MITOTIC_CELL_CYCLE	4	CDK1,CDC20,UBE2C,MAD2L1,BUB1B,AURKB
REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A	3.89	CDC20,UBE2C,MAD2L1,BUB1B
REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION	3.85	KIF2C,KIF23,KIF4A,RACGAP1,KIF11,KIF15
REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT	3.65	CDK1,CHEK1,CHEK2
REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR	3.64	CDK1,PIK3R1,ADCY9,PRKCE,GAB1,FGF2
REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION	3.57	CDC25A,CCNE1,CCNE2,CKS1B,PKMYT1
REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX	3.48	CDC6,E2F1,CDT1
REACTOME_G1_PHASE	3.43	E2F1,CDK4,CKS1B,CCND2
REACTOME_SIGNALING_BY_FGFR	3.39	CDK1,PIK3R1,ADCY9,PRKCE,GAB1,FGF2
REACTOME_SIGNALING_BY_RHO_GTPASES	3.37	RACGAP1,AKAP13,DLC1,RHOV,ARHGAP31,STARD13
REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_MITOTIC_PROTEINS	3.36	CDK1,CDC20,UBE2C,MAD2L1,BUB1B
REACTOME_LAGGING_STRAND_SYNTHESIS	3.14	PCNA,RFC4,DNA2
REACTOME_SIGNALING_BY_FGFR_IN_DISEASE	3.11	CDK1,PIK3R1,ADCY9,PRKCE,GAB1,FGF2
REACTOME_CDT1_ASSOCIATION_WITH_THE_CDC6_ORC_ORIGIN_COMPLEX	2.84	MCM8,CDC6,ORC6,CDT1
REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_CYCLIN_B	2.78	CDK1,CDC20,UBE2C
REACTOME_ADAPTIVE_IMMUNE_SYSTEM	2.76	PIK3R1,CDC20,UBE2C,KIF2C,KIF23,KIF4A,RACGAP1,KIF11,KIF15,RNF144B,UBE2S,ZBTB16
REACTOME_HEMOSTASIS	2.76	PIK3R1,PRKCE,KIF2C,KIF23,KIF4A,RACGAP1,KIF11,KIF15,SLC7A5,GATA6,EHD2
REACTOME_SIGNALING_BY_ERBB2	2.76	CDK1,PIK3R1,ADCY9,PRKCE,GAB1
REACTOME_EXTENSION_OF_TELOMERES	2.74	PCNA,RFC4,DNA2
REACTOME_IMMUNE_SYSTEM	2.69	CDK1,PIK3R1,CDC20,UBE2C,KIF2C,KIF23,FOS,KIF4A,RACGAP1,KIF11,KIF15,RNF144B,UBE2S,ZBTB16,IL6,MAP3K3,KPNA2
REACTOME_SIGNALING_BY_EGFR_IN_CANCER	2.62	CDK1,PIK3R1,ADCY9,PRKCE,GAB1
REACTOME_METABOLISM_OF_NUCLEOTIDES	2.46	RRM2,PAICS,CAT,CAD
REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES	2.39	CDK1,TUBG1
REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND	2.39	PCNA,DNA2
REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE	2.21	CDK1,PIK3R1,ADCY9,PRKCE,NTRK2
REACTOME_INSULIN_RECEPTOR_SIGNALLING_CASCADE	2.19	CDK1,PIK3R1,GAB1,FGF2
REACTOME_POL_SWITCHING	2.19	PCNA,RFC4
REACTOME_SIGNALING_BY_FGFR_MUTANTS	2.18	PIK3R1,GAB1,FGF2
REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER	2.14	PCNA,RFC4
REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_LAGGING_STRAND	2.08	PCNA,DNA2
REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION	2.06	CDK1,PIK3R1,ADCY9,PRKCE
REACTOME_SIGNALLING_BY_NGF	2.01	CDK1,PIK3R1,ADCY9,PRKCE,AKAP13,NTRK2
REACTOME_P53_INDEPENDENT_G1_S_DNA_DAMAGE_CHECKPOINT	2.01	CDC25A,CHEK1,CHEK2
REACTOME_PHOSPHOLIPASE_C_MEDIATED_CASCADE	1.95	ADCY9,PRKCE,FGF2
REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR	1.94	PIK3R1,GAB1
REACTOME_PI_3K_CASCADE	1.91	PIK3R1,GAB1,FGF2
REACTOME_SCFSKP2_MEDIATED_DEGRADATION_OF_P27_P21	1.91	CCNE1,CCNE2,CKS1B
REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY	1.9	TUBB3,TUBB2B
REACTOME_SIGNALING_BY_ILS	1.89	CDK1,PIK3R1,IL6,MAP3K3
REACTOME_SIGNALING_BY_INSULIN_RECEPTOR	1.88	CDK1,PIK3R1,GAB1,FGF2
REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC	1.79	TUBB3,TUBB2B
REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE	1.79	CDC20,UBE2C
REACTOME_MEIOSIS	1.78	CDK4,BRCA1,LMNB1,SYNE1
REACTOME_SIGNALING_BY_BMP	1.76	BMPR2,CHRDL1
REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING	1.76	PPP1R15A,TGFBR2
REACTOME_PHOSPHORYLATION_OF_THE_APC_C	1.76	CDK1,UBE2C
REACTOME_SIGNALING_BY_PDGF	1.71	CDK1,PIK3R1,ADCY9,PRKCE
REACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS	1.66	PPP1R15A,TGFBR2
REACTOME_PI3K_CASCADE	1.65	PIK3R1,GAB1,FGF2
REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1	1.63	CDC20,UBE2C,AURKB
REACTOME_MEIOTIC_SYNAPSIS	1.62	BRCA1,LMNB1,SYNE1
REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC	1.61	TUBB3,TUBB2B
REACTOME_DIABETES_PATHWAYS	1.59	HDGF,ASNS,IGF2BP1,IGF2BP3
REACTOME_TELOMERE_MAINTENANCE	1.59	PCNA,RFC4,DNA2
REACTOME_GLYCOLYSIS	1.58	GPI,TPI1
REACTOME_SIGNALING_BY_FGFR1_MUTANTS	1.56	PIK3R1,FGF2
REACTOME_SIGNALING_BY_SCF_KIT	1.55	CDK1,PIK3R1,CHEK1
REACTOME_DAG_AND_IP3_SIGNALING	1.51	ADCY9,PRKCE
REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION	1.5	CDC20,UBE2C,RNF144B,UBE2S,ZBTB16
REACTOME_PURINE_METABOLISM	1.48	PAICS,CAT
REACTOME_GLUCONEOGENESIS	1.46	GPI,TPI1
REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT	1.46	CFTR,ABCA6
REACTOME_GLOBAL_GENOMIC_NER_GG_NER	1.44	PCNA,RFC4
REACTOME_FRS2_MEDIATED_CASCADE	1.42	CDK1,FGF2
REACTOME_GAB1_SIGNALOSOME	1.38	PIK3R1,GAB1
REACTOME_IL_2_SIGNALING	1.32	CDK1,PIK3R1
REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM	1.29	RORA,FHL2,ACADL,ELOVL6
REACTOME_METABOLISM_OF_CARBOHYDRATES	1.27	GPI,TPI1,UST,CHPF2,B4GALT3
REACTOME_PI3K_EVENTS_IN_ERBB2_SIGNALING	1.27	PIK3R1,GAB1
REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS	1.27	ADCY9,PRKCE
REACTOME_TRANSCRIPTION_COUPLED_NER_TC_NER	1.25	PCNA,RFC4
REACTOME_AXON_GUIDANCE	1.24	CDK1,KIF4A,GFRA1,MYH11,SEMA5A
REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION	1.24	CDC20,UBE2C,RNF144B,UBE2S,ZBTB16
REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM	1.19	UST,CHPF2
REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY	1.19	RORA,NR3C2
REACTOME_GLYCOSAMINOGLYCAN_METABOLISM	1.18	UST,CHPF2,B4GALT3
REACTOME_MAP_KINASE_ACTIVATION_IN_TLR_CASCADE	1.18	CDK1,FOS
REACTOME_DNA_REPAIR	1.17	PCNA,RFC4,BRCA1
REACTOME_NUCLEOTIDE_EXCISION_REPAIR	1.16	PCNA,RFC4
REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM	1.14	CDK1,PIK3R1,IL6,MAP3K3,KPNA2
REACTOME_PROTEIN_FOLDING	1.13	TUBB3,TUBB2B
REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES	1.08	CXCL2,CXCL16
REACTOME_P53_DEPENDENT_G1_DNA_DAMAGE_RESPONSE	1.08	CCNE1,CCNE2
REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES	1.06	CDK1,TUBG1
REACTOME_GASTRIN_CREB_SIGNALLING_PATHWAY_VIA_PKC_AND_MAPK	1.05	CDK1,PIK3R1,PRKCE,EDN1
REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX	1.01	PPP1R15A,TGFBR2
REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH	1	CDK1,GFRA1
REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE	1	CENPN,HJURP
REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES	0.98	CDK1,TUBG1
REACTOME_SEMAPHORIN_INTERACTIONS	0.96	MYH11,SEMA5A
REACTOME_GLUCOSE_METABOLISM	0.95	GPI,TPI1
REACTOME_NFKB_AND_MAP_KINASES_ACTIVATION_MEDIATED_BY_TLR4_SIGNALING_REPERTOIRE	0.92	CDK1,FOS
REACTOME_TRIF_MEDIATED_TLR3_SIGNALING	0.9	CDK1,FOS
REACTOME_G_ALPHA1213_SIGNALLING_EVENTS	0.9	PIK3R1,AKAP13
REACTOME_TRAF6_MEDIATED_INDUCTION_OF_NFKB_AND_MAP_KINASES_UPON_TLR7_8_OR_9_ACTIVATION	0.87	CDK1,FOS
REACTOME_DEVELOPMENTAL_BIOLOGY	0.84	CDK1,CDK4,KIF4A,GFRA1,MYH11,SEMA5A
REACTOME_UNFOLDED_PROTEIN_RESPONSE	0.84	HDGF,ASNS
REACTOME_MYD88_MAL_CASCADE_INITIATED_ON_PLASMA_MEMBRANE	0.82	CDK1,FOS
REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES	0.81	ADCY9,SLC7A5,CFTR,ABCA6,SLC29A4,CYBRD1
REACTOME_MEIOTIC_RECOMBINATION	0.8	CDK4,BRCA1
REACTOME_SIGNALING_BY_ERBB4	0.77	CDK1,PIK3R1
REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL	0.76	PIK3R1,SLC7A5
REACTOME_ACTIVATED_TLR4_SIGNALLING	0.74	CDK1,FOS
REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS	0.71	PIK3R1,PRKCE,EDN1
REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS	0.7	EDN1,CXCL2,CXCL16
REACTOME_SIGNALING_BY_NOTCH	0.68	E2F1,HEYL
REACTOME_G_ALPHA_I_SIGNALLING_EVENTS	0.67	ADCY9,CXCL2,CXCL16
REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION	0.67	RORA,FHL2
REACTOME_TOLL_RECEPTOR_CASCADES	0.6	CDK1,FOS
REACTOME_G_ALPHA_S_SIGNALLING_EVENTS	0.58	ADCY9,PTGER4
REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS	0.53	PIK3R1,RORA,FHL2,EPT1,ACADL,ELOVL6
REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS	0.49	EDN1,CXCL2,CXCL16,PTGER4
REACTOME_APOPTOSIS	0.46	E2F1,LMNB1
REACTOME_SIGNALING_BY_GPCR	0.34	CDK1,PIK3R1,ADCY9,PRKCE,EDN1,CXCL2,CXCL16,AKAP13,PTGER4
REACTOME_NEURONAL_SYSTEM	0.3	ADCY9,STX12,KCNK3
REACTOME_GPCR_DOWNSTREAM_SIGNALING	0.27	PIK3R1,ADCY9,PRKCE,EDN1,CXCL2,CXCL16,AKAP13,PTGER4
REACTOME_GPCR_LIGAND_BINDING	0.24	EDN1,CXCL2,CXCL16,PTGER4
REACTOME_PHOSPHOLIPID_METABOLISM	0.17	PIK3R1,EPT1
REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION	0.16	PIK3R1,PRKCE
REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT	0.14	SLC7A5,SLC29A4
REACTOME_METABOLISM_OF_PROTEINS	0	TUBB3,TUBB2B,B4GALT3,HSPD1
REACTOME_GENERIC_TRANSCRIPTION_PATHWAY	0	RORA,NR3C2
REACTOME_INNATE_IMMUNE_SYSTEM	0	CDK1,FOS