pathway	-log10(p-value)	genes
onco_sig_RB_P107_DN.V1_UP	16.23	CCNE1,RRM2,MCM6,STMN1,DNA2,MAD2L1,KIF4A,TUBG1,PCNA,CCNE2,CHAF1B,CCNF,MCM2,TRPV2,NCAPD2,ASF1B,MCM7,E2F1,ORC6
onco_sig_VEGF_A_UP.V1_DN	16.13	DKK1,CCNE1,RRM2,IL6,GATA6,DBF4,BIRC5,LMNB1,BUB1,MCM4,MAD2L1,CKS2,KIF23,PTPRD,TTK,CCNB2,PLCL1,KIF11,BUB1B,EXO1,RFC4
onco_sig_RPS14_DN.V1_DN	14.14	ASNS,CYBRD1,TUBB2B,CDC6,CAD,DEPDC1,TUBG1,MYBL2,CDC20,KIF23,EMP2,CCNB2,KIF2C,MKI67,EXO1,KIF15,KANK2,ESPL1,MRPL12
onco_sig_PRC2_EZH2_UP.V1_UP	13.83	AURKB,EZH2,HOXA10,CDC25A,DNA2,LMNB1,BUB1,DEPDC1,KIF4A,MYBL2,PTPRD,TTK,MCM2,CENPF,CDT1,RFC4,TACC3,KIF15,HJURP
onco_sig_CORDENONSI_YAP_CONSERVED_SIGNATURE	9.77	DLC1,SDPR,TOP2A,BIRC5,STMN1,CDC20,EMP2,FGF2,CENPF,TNS1
onco_sig_RB_DN.V1_UP	9.49	BTG2,CCNE1,RRM2,MCM6,STMN1,DNA2,TUBG1,PCNA,CCNE2,PRKCE,DSN1,MCM7,TIMELESS
onco_sig_CSR_LATE_UP.V1_UP	9.37	EZH2,RRM2,CLSPN,UBE2C,CDK1,BIRC5,CDC6,TUBG1,CHEK2,MYBL2,LMNB2,UHRF1,CDC7,PAICS
onco_sig_GCNP_SHH_UP_LATE.V1_UP	8.08	CCND2,LOXL2,AURKB,RRM2,MCM6,TOP2A,CDK1,CDC25A,CHEK1,MCM4,CKS2,PSMC3IP,KIF2C
onco_sig_E2F1_UP.V1_UP	7.92	AURKB,EZH2,GATA6,TOP2A,DBF4,DNA2,LMNB1,BUB1,CHEK1,MCM4,CAD,CHAF1B,MAP3K3
onco_sig_PRC2_EDD_UP.V1_UP	6.91	CLSPN,RECQL4,CAD,KIF4A,MYBL2,KIF23,CHAF1B,MCM2,BUB1B,C16orf59,ASF1B,TACC3
onco_sig_ERB2_UP.V1_DN	5.1	GFRA1,DLC1,FHL2,DBF4,DTL,PUS1,DEPDC1,MAD2L1,TTK,NCAPG
onco_sig_MTOR_UP.V1_UP	4.78	RRM2,MCM6,UBE2C,DBF4,CDK1,STMN1,CDC20,PCNA,UHRF1
onco_sig_RB_P130_DN.V1_UP	4.68	AURKB,UBE2C,CDK1,BIRC5,CCNB2,ERG,CDC7,RACGAP1
onco_sig_TBK1.DF_DN	3.79	FOS,CCND2,SDPR,DKK1,BMPR2,LMNB1,CCNE2,DSN1,CDCA4,IGF2BP3
onco_sig_KRAS.DF.V1_UP	3.61	LOXL2,AURKB,DKK1,RRAD,GATA6,BMPR2,CAT,DSN1
onco_sig_PDGF_UP.V1_UP	3.59	FOS,SLC7A5,KCNK3,CCNE1,NCKAP1L,CDC25A,CDC6
onco_sig_BMI1_DN.V1_UP	3.57	EDN1,SLC7A5,DKK1,CLSPN,GPRC5A,LTBP4,SEMA3G
onco_sig_CSR_LATE_UP.V1_DN	3.21	GFRA1,BTG2,SDPR,ELOVL6,ABCA6,TSKU,RASSF2
onco_sig_GCNP_SHH_UP_EARLY.V1_UP	3.15	LOXL2,AURKB,MCM6,TOP2A,CHEK1,KIF4A,CKS2
onco_sig_TBK1.DN.48HRS_UP	3.01	EDN1,CXCL2,CHEK2,CDK4
onco_sig_ESC_V6.5_UP_LATE.V1_UP	2.94	LOXL2,DKK1,GATA6,RECK,NARF,PRICKLE1,CTDSPL
onco_sig_IL15_UP.V1_UP	2.91	FOS,SLC7A5,CCNE1,PUS1,CDC25A,KIF1C,NOP2
onco_sig_ALK_DN.V1_UP	2.83	SLC7A5,ASNS,IL6,CLSPN,CFTR,MTHFD2
onco_sig_SIRNA_EIF4GI_DN	2.79	LOXL2,CDC6,PSMC3IP,CFTR,SRPK1
onco_sig_NFE2L2.V2	2.66	ASNS,RRM2,DBF4,UCHL1,PTPRD,EMP2,TSKU,MTHFD2,HJURP,SEMA3G,TRIM16L
onco_sig_STK33_NOMO_UP	2.49	FOS,CXCL2,BTG2,ZFP36,PPP1R15A,STX12,OTUD1,PTGFRN
onco_sig_STK33_UP	2.49	FOS,CXCL2,BTG2,CYBRD1,ZFP36,PPP1R15A,STX12,OTUD1
onco_sig_ESC_J1_UP_EARLY.V1_UP	2.35	PTGER4,LOXL2,ZBTB16,AKR1C2,PIK3R1,NARF
onco_sig_CYCLIN_D1_UP.V1_DN	2.26	EZH2,NCKAP1L,PIK3R1,GAB1,ERG,RBMS2
onco_sig_IL2_UP.V1_UP	2.25	FOS,SLC7A5,PUS1,CDC25A,KIF1C,EHD2
onco_sig_E2F1_UP.V1_DN	2.24	CCND2,GFRA1,SDPR,ADARB1,NPR1,B4GALT3
onco_sig_HOXA9_DN.V1_DN	2.22	ELOVL6,CDC6,CDT1,NCAPD2,FANCI,CEP55
onco_sig_EGFR_UP.V1_DN	2.21	GFRA1,DLC1,EZH2,DTL,DEPDC1,KIF11
onco_sig_E2F3_UP.V1_UP	2.21	CCNE1,DTL,RECQL4,PCNA,CCNE2,BRI3BP
onco_sig_MTOR_UP.N4.V1_UP	2.21	SLC7A5,ASNS,ELOVL6,ADARB1,DNMT3B,RBM28
onco_sig_CAMP_UP.V1_DN	2.17	CCND2,RRAD,TUBB2B,ZFP36,PTPRD,TUBB3
onco_sig_CAMP_UP.V1_UP	2.17	FOS,PPP1R15A,MAD2L1,MTHFD2,SRPK1,CHAF1A
onco_sig_MEL18_DN.V1_UP	2.16	EDN1,SLC7A5,CLSPN,TGFBR3,LTBP4
onco_sig_KRAS.KIDNEY_UP.V1_UP	2.12	CCND2,GPM6A,PLCL1,SOBP,TMEM100
onco_sig_HINATA_NFKB_IMMU_INF	1.99	CXCL2,IL6
onco_sig_ESC_V6.5_UP_EARLY.V1_UP	1.85	DLC1,NARF,PRICKLE1,SLC29A4,MAGI3
onco_sig_SRC_UP.V1_DN	1.76	PTGER4,EZH2,MCM4,UHRF1,RACGAP1
onco_sig_ESC_J1_UP_LATE.V1_DN	1.7	EDN1,DLC1,TUBB2B,LMNB2,TUBB3
onco_sig_LEF1_UP.V1_DN	1.67	CXCL2,GATA6,CFTR,CAT,PLLP
onco_sig_ESC_J1_UP_LATE.V1_UP	1.66	LOXL2,FHL2,GATA6,PRICKLE1,TGFBR3
onco_sig_PTEN_DN.V1_UP	1.66	EDN1,TUBB2B,UCHL1,NFASC,TGFBR3
onco_sig_P53_DN.V1_DN	1.65	GFRA1,BTG2,RASSF2,PTPRM,MITF
onco_sig_JNK_DN.V1_UP	1.65	RRAD,RASSF2,SYNE1,ACADL,STARD13
onco_sig_TGFB_UP.V1_UP	1.65	EDN1,DLC1,RRAD,BMPR2,UBL3
onco_sig_CYCLIN_D1_KE_.V1_DN	1.64	ADARB1,NCKAP1L,CFTR,PIK3R1,GAB1
onco_sig_PRC2_SUZ12_UP.V1_UP	1.64	CCNE1,HOXA10,RECQL4,CHEK1,LMNB2
onco_sig_MTOR_UP.N4.V1_DN	1.64	BTG2,CCNE1,ZBTB16,PLCL1,EVI2B
onco_sig_NOTCH_DN.V1_UP	1.64	BTG2,SDPR,RRAD,EFNA3,TNS1
onco_sig_GLI1_UP.V1_UP	1.64	CCND2,ZBTB16
onco_sig_LEF1_UP.V1_UP	1.63	CCND2,DKK1,CYBRD1,TUBB2B,TRPV2
onco_sig_KRAS.PROSTATE_UP.V1_DN	1.49	EDN1,RRAD,ZBTB16,SLC19A3
onco_sig_STK33_SKM_UP	1.48	FOS,BTG2,CYBRD1,ZFP36,STX12,PTPRM
onco_sig_TBK1.DF_UP	1.48	CXCL2,CYBRD1,STX12,AVL9,ADCY9,DNMT3B
onco_sig_KRAS.BREAST_UP.V1_UP	1.47	CXCL2,KCNK3,PPP1R15A,CASS4
onco_sig_P53_DN.V2_UP	1.45	CXCL2,KCNK3,NCKAP1L,PRKCE
onco_sig_RELA_DN.V1_UP	1.44	FOS,ZFP36,PPP1R15A,FGF2
onco_sig_PDGF_ERK_DN.V1_DN	1.44	CKS2,CCNF,EFNA3,MAP3K3
onco_sig_CSR_EARLY_UP.V1_DN	1.4	GFRA1,SDPR,HOXA10,OTUD1
onco_sig_SIRNA_EIF4GI_UP	1.34	BTG2,NCAPD2,HSPD1
onco_sig_SNF5_DN.V1_DN	1.32	RRAD,UCHL1,NPR1,EFNA3
onco_sig_PKCA_DN.V1_DN	1.3	CENPF,TRPV2,KANK2,FANCI
onco_sig_CAHOY_OLIGODENDROCUTIC	1.29	ELOVL6,SEMA5A,PLLP
onco_sig_AKT_UP.V1_UP	1.26	EDN1,UBE2C,CXCL16,RHOV
onco_sig_SNF5_DN.V1_UP	1.22	AURKB,UBE2C,DTL,BUB1
onco_sig_GCNP_SHH_UP_LATE.V1_DN	1.2	EDN1,PTGER4,PUS1,ADCY9
onco_sig_AKT_UP_MTOR_DN.V1_DN	1.18	SLC7A5,KCNK3,MCM6,CHRDL1
onco_sig_MTOR_UP.V1_DN	1.18	PTGER4,KCNK3,AOC3,MYH11
onco_sig_E2F3_UP.V1_DN	1.18	IL6,NCKAP1L,GPRC5A,CBX3
onco_sig_TBK1.DN.48HRS_DN	1.18	CDK1,BIRC5
onco_sig_AKT_UP.V1_DN	1.16	SLC7A5,KCNK3,ZEB1,RECK
onco_sig_PTEN_DN.V1_DN	1.16	GPM6A,ABCA6,NR3C2,HEYL
onco_sig_LTE2_UP.V1_UP	1.14	EDN1,PTGER4,UST,SECISBP2L
onco_sig_ERB2_UP.V1_UP	1.13	EDN1,PTGER4,AKR1C2,HOXB7
onco_sig_ATF2_S_UP.V1_UP	1.12	EZH2,TOP2A,SEMA5A,KIF23
onco_sig_TGFB_UP.V1_DN	1.12	CXCL2,PTGER4,SDPR,MITF
onco_sig_P53_DN.V1_UP	1.11	DKK1,FHL2,UCHL1,CAT
onco_sig_RAF_UP.V1_DN	1.11	FOS,GFRA1,DLC1,DKK1
onco_sig_PRC2_EZH2_UP.V1_DN	1.11	EDN1,NR3C2,MTMR10,TMEM100
onco_sig_HOXA9_DN.V1_UP	1.11	FOS,PTGER4,STX12,CHPF2
onco_sig_STK33_DN	1.04	ASNS,ELOVL6,HOXA10,GPM6A,CAD
onco_sig_STK33_NOMO_DN	1.03	ASNS,HOXA10,GPM6A,CHRDL1,SOBP
onco_sig_PTEN_DN.V2_UP	0.94	LOXL2,GPM6A,CHRDL1
onco_sig_ATM_DN.V1_UP	0.92	SLC7A5,ADARB1,RECQL4
onco_sig_P53_DN.V2_DN	0.92	BMPR2,RECK,CCNF
onco_sig_PDGF_ERK_DN.V1_UP	0.91	NCKAP1L,STX12,CHEK2
onco_sig_ATM_DN.V1_DN	0.9	BMPR2,DNAH9,NTRK2
onco_sig_PKCA_DN.V1_UP	0.78	TUBB2B,PSMC3IP,TSKU
onco_sig_ESC_V6.5_UP_EARLY.V1_DN	0.77	SDPR,FHL2,FGF2
onco_sig_ESC_J1_UP_EARLY.V1_DN	0.74	EDN1,ZFP36,EMP2
onco_sig_WNT_UP.V1_UP	0.73	FOS,AURKB,IL6
onco_sig_MYC_UP.V1_DN	0.72	IL6,PSMC3IP,GPRC5A
onco_sig_MYC_UP.V1_UP	0.7	FOS,PUS1,SLC29A4
onco_sig_CAHOY_ASTROCYTIC	0.7	ASNS,CHRDL1
onco_sig_CYCLIN_D1_KE_.V1_UP	0.69	ASNS,FHL2,TGFBR2
onco_sig_NOTCH_DN.V1_DN	0.69	TUBB2B,ZBTB16,ACADL
onco_sig_ATF2_UP.V1_UP	0.68	KCNK3,DTL,NCAPG
onco_sig_RPS14_DN.V1_UP	0.68	PTGER4,EVI2B,COLEC12
onco_sig_PRC2_EDD_UP.V1_DN	0.67	CCND2,AVL9,NR3C2
onco_sig_DCA_UP.V1_DN	0.67	CHEK2,NFASC,ASPM
onco_sig_LTE2_UP.V1_DN	0.66	GFRA1,DLC1,FHL2
onco_sig_MEK_UP.V1_DN	0.66	GFRA1,DLC1,ELOVL6
onco_sig_MEK_UP.V1_UP	0.66	EDN1,PTGER4,AKR1C2
onco_sig_RB_DN.V1_DN	0.56	SLC7A5,RHOV
onco_sig_RB_P107_DN.V1_DN	0.55	EDN1,ELOVL6
onco_sig_NRL_DN.V1_DN	0.52	LMNB2,CDT1
onco_sig_RB_P130_DN.V1_DN	0.5	RHOV,AVL9
onco_sig_CTIP_DN.V1_DN	0.49	EDN1,CYBRD1
onco_sig_KRAS.KIDNEY_UP.V1_DN	0.49	IL6,SEMA5A
onco_sig_PTEN_DN.V2_DN	0.48	STMN1,RECQL4
onco_sig_BMI1_DN_MEL18_DN.V1_UP	0.48	EDN1,SLC7A5
onco_sig_BMI1_DN.V1_DN	0.48	FOS,SFXN1
onco_sig_KRAS.BREAST_UP.V1_DN	0.48	NPR1,SOBP
onco_sig_KRAS.LUNG.BREAST_UP.V1_UP	0.48	CXCL2,DNAH9
onco_sig_KRAS.PROSTATE_UP.V1_UP	0.48	ZEB1,PLLP
onco_sig_ALK_DN.V1_DN	0.46	FOS,C16orf59
onco_sig_STK33_SKM_DN	0.29	ASNS,ELOVL6,CXCL16
onco_sig_KRAS.600_UP.V1_DN	0.29	EDN1,RRAD,ZBTB16
onco_sig_KRAS.600.LUNG.BREAST_UP.V1_UP	0.29	CXCL2,PPP1R15A,DNAH9
onco_sig_CYCLIN_D1_UP.V1_UP	0.18	FHL2,MKI67
onco_sig_AKT_UP_MTOR_DN.V1_UP	0.18	EDN1,CXCL16
onco_sig_ATF2_S_UP.V1_DN	0.18	FOS,ADARB1
onco_sig_ATF2_UP.V1_DN	0.18	FOS,CYBRD1
onco_sig_JAK2_DN.V1_UP	0.18	SEMA5A,ZEB1
onco_sig_EGFR_UP.V1_UP	0.17	EDN1,LOXL2
onco_sig_RAPA_EARLY_UP.V1_DN	0.17	PRKCE,AOC3
onco_sig_PIGF_UP.V1_DN	0.17	CDC20,NFASC
onco_sig_VEGF_A_UP.V1_UP	0.17	ADARB1,SEMA5A
onco_sig_PRC1_BMI_UP.V1_DN	0.17	EDN1,CCND2
onco_sig_PRC1_BMI_UP.V1_UP	0.17	HOXA10,CLSPN
onco_sig_PRC2_SUZ12_UP.V1_DN	0.17	EDN1,MTMR10
onco_sig_JNK_DN.V1_DN	0.17	UBE2C,NPR1
onco_sig_IL21_UP.V1_UP	0.17	SLC7A5,ABCA6
onco_sig_KRAS.DF.V1_DN	0.17	UCHL1,SYNE1
onco_sig_KRAS.600_UP.V1_UP	0	KCNK3,ZEB1