pathway	-log10(p-value)	genes
onco_sig_RB_P107_DN.V1_UP	22.14	E2F8,TEK,DUSP1,CDC45,CCNE1,RRM2,SLIT3,MCM6,NCAPH,PRC1,FEN1,STMN1,DNA2,MAD2L1,KIF4A,RPL39L,COL1A1,FANCA,TUBG1,PCNA,POLE,CCNE2,CHAF1B,TCF19,CDH2,CCNF,MCM2,TRPV2,NCAPD2,MRGPRF,FKBP10,CENPH,ASF1B,MCM7,GINS4,E2F1,ORC6,GTSE1
onco_sig_PRC2_EZH2_UP.V1_UP	16.32	CXCL12,AURKB,CDC45,MXD3,EZH2,LMOD1,HOXA10,AFF3,NCAPH,CDC25A,PTPRD,SULF1,DNA2,LMNB1,BUB1,DEPDC1,KIF4A,SKP2,MYBL2,HELLS,HMMR,RAD54L,TTK,LRRC32,CACNA2D2,PEAK1,MCM2,PSRC1,CENPF,CDT1,RFC4,TACC3,THBS2,KIF15,HJURP,DSCC1
onco_sig_CSR_LATE_UP.V1_UP	16.22	IL7R,CXCL12,EZH2,RRM2,CLSPN,UBE2C,FEN1,CDK1,ZWILCH,BIRC5,CDC6,TRIP13,SSTR1,FANCA,TUBG1,CHEK2,MYBL2,LMNB2,ZNF367,MET,TCF19,UHRF1,HN1,CDCA8,FOXM1,CDH2,ANLN,NUF2,ZWINT,CCDC34,CDC7,NETO2,PAICS,FAM83D
onco_sig_CORDENONSI_YAP_CONSERVED_SIGNATURE	15.69	ANKRD1,DAB2,DLC1,SDPR,TK1,DUSP1,TGFB2,CTGF,TOP2A,AXL,BIRC5,STMN1,CDC20,HMMR,EMP2,FGF2,SLIT2,LHFP,CENPF,TNS1,PDLIM2,COL4A3
onco_sig_RPS14_DN.V1_DN	14.51	E2F8,ASNS,TK1,CYBRD1,TUBB2B,SUV39H2,ORC1,NCAPH,PRC1,ZWILCH,CDC6,CAD,DEPDC1,TRIP13,REPS2,TUBG1,MYBL2,CDC20,KIF23,RGS5,ATAD2,PYCR1,EMP2,CCNB2,KIF2C,MKI67,EXO1,KIF15,KANK2,ARHGAP11A,MYO19,ESPL1,MRPL12
onco_sig_VEGF_A_UP.V1_DN	14.17	ITGA2,DKK1,CDC45,CCNE1,GATA6,RRM2,IL6,STEAP1,DBF4,PTPRD,BIRC5,ACE,PLCL1,LMNB1,BUB1,MCM4,MAD2L1,CKS2,MEST,KIF23,HMMR,BUB1B,CDKN3,RGS5,TTK,CCNB2,KIF11,MMRN1,PCDH7,EXO1,RFC4,CENPA,CCNB1
onco_sig_PRC2_EDD_UP.V1_UP	10.6	CXCL12,CDC45,LMOD1,CLSPN,AFF3,ORC1,ZWILCH,RECQL4,DBF4B,CAD,KIF4A,MYBL2,WFDC1,HELLS,KIF23,BUB1B,RAD54L,CHAF1B,SLC12A4,CDCA8,PEAK1,SV2A,MCM2,C16orf59,UTRN,ASF1B,TACC3,PCDHGC3
onco_sig_ATF2_S_UP.V1_DN	9.53	FOS,PID1,SLC39A8,ABCC3,EFEMP1,AK4,SLIT3,IL33,ADARB1,TPD52,SVEP1,PLSCR4,KCNAB2,ITIH5,SLC12A8,CBX7,TCF21,ABCA8,RGS5,CD302,POLE,COL11A1,ADH1B,CELF2,SFRP4,SORBS1
onco_sig_ATF2_UP.V1_DN	9.53	FOS,CXCL12,PID1,SLC39A8,ABCC3,EFEMP1,AK4,SLIT3,IL33,CYBRD1,TPD52,LIMCH1,SVEP1,PKP2,PLSCR4,WISP1,ITIH5,SLC12A8,HKDC1,TCF21,ABCA8,CD302,FRY,CELF2,MFAP4,SFRP4
onco_sig_E2F1_UP.V1_UP	9.44	EFNB2,E2F8,AURKB,TK1,EZH2,GATA6,TPD52,SIRPA,KANK3,NCAPH,TOP2A,PRC1,DBF4,FEN1,DNA2,LMNB1,BUB1,PTPN21,CHEK1,MCM4,CAD,CHAF1B,MAP3K3,MFI2,E2F3,HMGB3
onco_sig_NFE2L2.V2	9.13	CXCL12,SLC7A11,GAS7,TSPAN7,ASNS,CDC45,RRM2,ACVRL1,NCF2,DMD,KIAA0040,SUV39H2,ORC1,DBF4,PTPRD,C1orf21,UCHL1,DBF4B,REPS2,ZNF367,EMP2,IL18R1,TSKU,TFRC,SPN,MTHFD2,MFI2,PPAT,HJURP,SEMA3G,TPPP3,FIGF,RTKN2,HLA-DOA,PFN2,NLN,KCNE4,SFTPA1,GCLC,ADAMTS12,OSCAR,TRIM16L
onco_sig_BMI1_DN.V1_UP	8.69	EDN1,HBEGF,IL7R,SLC7A5,STX1A,LCP1,DKK1,ADAM12,TEK,ADRB2,PODXL,TGFB2,SIRPA,CLSPN,SLC2A1,FAP,GPRC5A,LRRC15,LTBP4,SEMA3G,GABRE,SLC5A6
onco_sig_STK33_NOMO_UP	8.02	FOS,IL7R,EGR3,MMP1,PLAU,THBD,EFNB2,CXCL2,PID1,DAB2,BTG2,OLR1,DUSP1,EPAS1,KMO,ZFP36,PPP1R15A,ACP5,MAFF,COL6A3,STX12,RAB8B,ZEB2,OTUD1,FBXO32,LIMK1,C20orf194,CSRNP1,TPSAB1,PTGFRN
onco_sig_KRAS.PROSTATE_UP.V1_UP	6.86	ITGA2,IL7R,NR4A3,JAM2,ARHGAP24,HKDC1,LRCH1,TPK1,CX3CL1,ZEB1,LRRC15,PLLP,FOXF2,RARRES2,THSD4,SYNPO2,HABP2,C17orf53,GRK5
onco_sig_P53_DN.V1_UP	6.75	ITGA2,MMP1,PLAU,EFNB2,ANKRD1,APBB2,DKK1,EFEMP1,PODXL,FHL2,LAMP3,DMD,MAFF,AXL,SULF1,UCHL1,MEST,SLIT2,CAT,TPBG,VIPR1,CNR1
onco_sig_HOXA9_DN.V1_DN	6.71	RGS16,E2F8,ELOVL6,CDC45,HMGCS1,ORC1,CDC6,GINS1,EPB41L2,HELLS,ATAD2,GPM6B,NRGN,MFAP4,SV2A,CDT1,NCAPD2,FANCI,GINS4,ARHGAP11A,MEIS1,CEP55
onco_sig_GCNP_SHH_UP_LATE.V1_UP	6.54	E2F8,LOXL2,CCND2,AURKB,VCAN,TK1,RRM2,FOXA1,MCM6,TOP2A,PRC1,CDK1,CDC25A,CHEK1,MCM4,CKS2,PSMC3IP,TRIP13,AURKA,SIX4,KIF2C
onco_sig_STK33_UP	6.47	FOS,HBEGF,EGR3,MMP1,PLAU,THBD,SLC7A11,CXCL2,PID1,BTG2,OLR1,DUSP1,KMO,NCF2,CYBRD1,CD36,ZFP36,PPP1R15A,MAFF,COL6A3,STX12,C10orf54,ZEB2,OTUD1,LIMK1,C20orf194,CSRNP1
onco_sig_CSR_LATE_UP.V1_DN	6.42	GFRA1,BTG2,SDPR,ELOVL6,HMGCS1,DRAM1,PDE5A,ACVRL1,SVEP1,C10orf54,DKK2,TNXB,ABCA6,TSKU,RASSF2,NTN4,MRGPRF,MAMDC2,FIBIN,F8
onco_sig_MTOR_UP.V1_UP	6.42	HMGCS1,RRM2,AK4,MCM6,UBE2C,STEAP1,DBF4,SLC2A1,CDK1,STMN1,CDC20,HELLS,PCNA,TCF19,UHRF1,HN1,TFRC,DUOXA1,SIGLEC1,MS4A7
onco_sig_LTE2_UP.V1_UP	6.3	EDN1,PTGER4,DAB2,TK1,ABCC3,GPX3,HMGCS1,EPAS1,DRAM1,TNS3,KMO,SASH1,CDKN3,CD302,RCAN1,VTCN1,ABCG2,PHACTR2,DPYSL2,UST,SECISBP2L
onco_sig_MEL18_DN.V1_UP	6.3	EDN1,HBEGF,IL7R,SLC7A5,SLC7A11,STX1A,NTM,LCP1,ADAM12,TEK,TGFB2,CLSPN,WISP1,TGFBR3,ABLIM3,FAP,LTBP4,DDX11
onco_sig_P53_DN.V1_DN	6.23	THBD,GAS7,TSPAN7,GFRA1,BTG2,VCAN,NR4A3,ABCA4,SOCS3,ACP5,KCNAB2,FRMD4B,NR4A1,STOM,RASSF2,TRAF4,PTPRM,MITF,SOX4,ITGAL,GRAMD1B
onco_sig_E2F1_UP.V1_DN	6.2	CCND2,GFRA1,APBB2,DAB2,VCAN,SDPR,HMGCS1,ADARB1,SASH1,HES6,ADAMTS1,SYNPO,NPR1,TNXB,STOM,RUNX2,COL11A1,EFNA4,NHSL1,B4GALT3,TCF4
onco_sig_BMI1_DN_MEL18_DN.V1_UP	6.14	EDN1,HBEGF,IL7R,SLC7A5,SLC7A11,STX1A,NTM,APBB2,LCP1,ADAM12,TEK,ADRB2,PODXL,TGFB2,ABLIM3,FAP,ZEB2,LRRC15
onco_sig_E2F3_UP.V1_UP	6.1	CCNE1,PLSCR4,FEN1,DTL,LMO2,RECQL4,GINS1,FANCA,ZNF367,PCNA,POLE,CCNE2,ATAD2,ABCG2,TMOD2,CBX2,RTN4RL1,SBK1,SYNM,SEPT3,BRI3BP
onco_sig_RB_P130_DN.V1_UP	5.99	RGS16,AURKB,MYLK,TK1,UBE2C,ORC1,CDK1,RASGRF1,BIRC5,AURKA,ERG,TRAF4,CCNB2,CDC7,RACGAP1,RHOJ,FAM64A
onco_sig_AKT_UP.V1_DN	5.83	SLC7A5,KCNK3,NR4A3,EFEMP1,DPT,DRAM1,SLIT3,SASH1,ITIH5,LIMD1,OGN,TCF21,WIF1,ZEB1,EIF4E3,FBXO32,RECK,FMO2,SFRP2,SCARA5
onco_sig_RB_DN.V1_UP	5.83	BTG2,CCNE1,RRM2,MCM6,SPOCK1,STMN1,DNA2,TUBG1,PCNA,CCNE2,RAD54L,FXYD6,PRKCE,DSN1,DUOXA1,MCM7,TIMELESS
onco_sig_ESC_V6.5_UP_LATE.V1_UP	5.73	LOXL2,TSPAN7,DAB2,LCP1,DKK1,SLC39A8,PODXL,GPX3,GATA6,SLIT3,EGLN3,FOXA1,SPOCK2,CDH2,RECK,NARF,PRICKLE1,ZDHHC9,APLNR,CTDSPL
onco_sig_KRAS.DF.V1_UP	5.64	MMP1,PLAU,E2F8,LOXL2,PID1,RRAD,AURKB,DKK1,VCAN,GATA6,STEAP1,COL6A3,BMPR2,CHRNA5,CAT,DSN1,DPYSL2,FLRT3,PDLIM2,BORA
onco_sig_PRC2_EZH2_UP.V1_DN	5.61	EDN1,HBEGF,ITGA2,KLF4,RGS16,TSPAN7,ETV1,IL33,DMD,KLF13,ABLIM3,IRF8,RASL12,DKK2,GPM6B,FXYD6,NR3C2,MTMR10,TMEM100,PTPRB
onco_sig_ESC_V6.5_UP_EARLY.V1_DN	5.19	HBEGF,PLAU,KLF4,SDPR,CAV1,CTGF,FHL2,SOCS3,AXL,CRY2,CD37,FAP,COL1A1,COL11A1,FGF2,KIF18A,CCDC34,AHNAK
onco_sig_PTEN_DN.V1_UP	5.15	EDN1,NR4A3,IL33,TUBB2B,KANK3,HOXD1,SPOCK1,JAM3,SPOCK2,TGFBR3,UCHL1,RASL12,LRCH1,CD27,GDF10,AQP1,FAM49A,NFASC,MMRN2
onco_sig_STK33_SKM_UP	5.08	FOS,HBEGF,PLAU,THBD,SLC7A11,PID1,BTG2,OLR1,DUSP1,ETV1,KMO,NCF2,CYBRD1,CD36,ZFP36,STX12,C10orf54,CYBB,PTPRM,TMOD2,EPB41L5,MFAP3L,FGD4,SH2B3
onco_sig_LEF1_UP.V1_UP	5.04	EGR3,CCND2,NELL2,DKK1,CYBRD1,TUBB2B,MAOB,AXL,LMO2,CD302,FHL1,TRPV2,FOXF2,WWC2,ADAMTS8,PDZD2,ZFPM2,GNG4,TMEM47
onco_sig_SNF5_DN.V1_UP	5.03	AURKB,LCP1,UBE2C,DTL,ZWILCH,LMO2,BUB1,MEST,AGTR2,ABI3BP,NCAPG2,SFRP2,CD93,CX3CR1,FBLN1,FNDC1,KIAA1524,ZMYND19
onco_sig_ALK_DN.V1_UP	4.94	SLC7A5,SLC7A11,ASNS,ADAM12,ETV1,EPAS1,IL6,CLSPN,TBX2,SLC12A8,FAP,CFTR,MTHFD2,CCL19,SLAMF7,VSTM4
onco_sig_KRAS.KIDNEY_UP.V1_UP	4.94	TSPAN7,CCND2,ETV1,METTL7A,LIMCH1,PLSCR4,PLCL1,GPM6A,SOBP,WIF1,FZD3,SORBS1,RAPGEF4,TMEM100,SPARCL1,AQP4
onco_sig_PKCA_DN.V1_DN	4.79	PLAU,SLIT3,ABCA4,ECE2,ZEB2,PYCR1,EIF4E3,METTL1,ABI3BP,CENPF,TRPV2,CABYR,KANK2,RHOJ,FANCI,SLC46A2,CYGB
onco_sig_ESC_J1_UP_LATE.V1_UP	4.62	ANKRD1,LOXL2,DAB2,SLC39A8,PODXL,GPX3,GATA6,DRAM1,CTGF,FHL2,SPOCK1,TGFBR3,HKDC1,LMO7,PTPN21,PRICKLE1,ARAP2,ZDHHC9
onco_sig_IL15_UP.V1_UP	4.6	FOS,EGR3,CXCL12,SLC7A5,RGS16,CCNE1,ACVRL1,KANK3,MAFF,SPOCK1,PUS1,CDC25A,CD69,HEG1,SLAMF7,KIF1C,HABP2,NOP2
onco_sig_EGFR_UP.V1_UP	4.57	EDN1,HBEGF,ITGA2,MMP1,KLF4,RGS16,SLC7A11,LOXL2,COL5A2,ABCC3,EPAS1,DRAM1,TNS3,TGFB2,CTGF,EGLN3,RCAN1,ARAP2
onco_sig_CYCLIN_D1_KE_.V1_DN	4.54	IL7R,CXCL12,CAV1,DIO2,ADARB1,KIAA0040,NCKAP1L,MYO1F,CD37,CFTR,CD27,PIK3R1,ADH1B,VAMP2,MAPK4,GAB1,ANGPT1,PGM5
onco_sig_RAF_UP.V1_DN	4.54	FOS,EGR3,EFNB2,GFRA1,APBB2,DLC1,DKK1,MYLK,CAV1,SLC39A8,CBFA2T3,TGFB2,MYBL1,AK4,SELENBP1,EPB41L2,SOX4,NEDD4L
onco_sig_PRC2_SUZ12_UP.V1_UP	4.54	CCNE1,CBFA2T3,ACVRL1,LMOD1,HOXA10,ACP5,ORC1,ZWILCH,RECQL4,CHEK1,LMNB2,WFDC1,TSPAN12,RAD54L,CACNA2D2,LDB2,CCL19,MARK1
onco_sig_MEK_UP.V1_UP	4.49	EDN1,PLAU,KLF4,SLC7A11,PTGER4,COL5A2,ABCC3,GPX3,EPAS1,TNS3,EGLN3,LIMCH1,NEDD9,CAMK2N1,RAB8B,AKR1C2,LHFP,FHL1
onco_sig_CAMP_UP.V1_DN	4.38	IL7R,NTM,RRAD,CCND2,NCF2,TUBB2B,SVEP1,ZFP36,PTPRD,SPOCK2,FRY,CELF2,SLC15A2,FOSB,TUBB3,TTYH3,DST,GNAQ
onco_sig_SNF5_DN.V1_DN	4.34	RGS16,ANKRD1,RRAD,MYLK,OLR1,EFEMP1,GPX3,DIO2,ABCA4,LMOD1,PKP2,FLT4,UCHL1,NPR1,RGS5,EFNA3
onco_sig_ESC_J1_UP_EARLY.V1_UP	4.33	CXCL12,PTGER4,LOXL2,DAB2,ZBTB16,KANK3,HES6,C10orf54,ECE2,AKR1C2,PIK3R1,NARF,NHSL1,ZFPM2,NEK2,FGF14,MOCS1
onco_sig_CRX_DN.V1_UP	4.1	GAS7,MYLK,ABCA4,WISP1,SUV39H2,SELENBP1,PTPN21,BUB1B,AQP1,RNF207,RHPN1,RAD51,SYNPO2,WDR78
onco_sig_ATF2_S_UP.V1_UP	4.07	MMP1,PLAU,EFNB2,TK1,ADRB2,TRPM2,EZH2,HOXD1,TOP2A,SEMA5A,ABLIM3,RPL39L,KIF23,CDKN3,FOXM1,FAM107A,FAT4
onco_sig_IL2_UP.V1_DN	3.99	TSPAN7,TEK,MYLK,TNS3,METTL7A,PLCL1,HKDC1,RASL12,KIAA1462,CD34,SESN1,SLA,SEMA6D,FZD3,EFNA4,MYCT1,ARHGAP6
onco_sig_AKT_UP_MTOR_DN.V1_DN	3.83	SLC7A5,COL5A2,VCAN,KCNK3,NR4A3,EFEMP1,DPT,SASH1,MCM6,STEAP1,LIMD1,CHRDL1,OGN,EIF4E3,FKBP10,CADM3
onco_sig_TBK1.DF_DN	3.82	FOS,ITGA2,CCND2,COL5A2,DKK1,SDPR,SLC39A8,HMGCS1,KLF13,CAMK2N1,BMPR2,LMNB1,CCNE2,STOM,DSN1,ZWINT,FLRT3,CDCA4,KIF14,IGF2BP3,MPHOSPH9
onco_sig_MTOR_UP.V1_DN	3.8	PTGER4,STX1A,NELL2,KCNK3,DUSP1,SLIT3,SASH1,CRY2,ITIH5,WIF1,WFDC1,SLC12A4,FBXO32,AOC3,ADAMTS8,MYH11
onco_sig_TBK1.DN.48HRS_UP	3.71	EDN1,CXCL2,MYLK,CHEK2,PSRC1,CDK4,MTFR1,KIAA0907
onco_sig_LEF1_UP.V1_DN	3.66	EFNB2,CXCL2,OLR1,MXD3,GATA6,TNS3,CTGF,IL33,LIMCH1,FOXA1,PLSCR4,SELENBP1,CFTR,CAT,DIXDC1,PLLP
onco_sig_CYCLIN_D1_UP.V1_DN	3.63	IL7R,RGS16,CAV1,EZH2,TPD52,KIAA0040,NCKAP1L,ALOX5,MYO1F,SSTR1,SLC6A4,PIK3R1,ERG,VAMP2,GAB1,RBMS2
onco_sig_RPS14_DN.V1_UP	3.61	EGR3,PLAU,PTGER4,ANKRD1,PID1,NR4A3,KMO,NCF2,SIRPA,MYO1F,CD69,FRY,SESN1,ITGAL,EVI2B,COLEC12
onco_sig_GCNP_SHH_UP_EARLY.V1_UP	3.56	E2F8,LOXL2,AURKB,MCM6,ADAMTS1,TOP2A,PRC1,FEN1,CHEK1,KIF4A,CKS2,RPL39L,AURKA,E2F3,ANLN
onco_sig_EGFR_UP.V1_DN	3.52	EGR3,EFNB2,E2F8,GFRA1,APBB2,DLC1,CAV1,SLC39A8,EZH2,CBFA2T3,DTL,DEPDC1,EPB41L2,NCAPG2,KIF11,SPTBN1
onco_sig_P53_DN.V2_UP	3.23	CXCL12,CXCL2,ADAM12,KCNK3,NCKAP1L,CD69,BARX2,PRKCE,SLA,SLC15A2,LRRC32,ITM2A,NFIX
onco_sig_MEL18_DN.V1_DN	3.23	FOS,PID1,GAS7,PDE5A,DIO2,DMD,PKP2,MAOB,SULF1,FRMD4B,NDRG2,ZCCHC24,GNG7
onco_sig_RELA_DN.V1_UP	3.21	FOS,EGR3,THBD,NTM,GAS7,KMO,PDE5A,ZFP36,PPP1R15A,LMO7,AGPAT4,FGF2,FOSB
onco_sig_GCNP_SHH_UP_EARLY.V1_DN	3.2	LCP1,CBFA2T3,FOXA1,CNN1,JAM3,C4orf32,ADCY9,SLC6A4,AGTR2,WWC2,SIX4,CDK5RAP3,HTRA3,ANKRD44
onco_sig_ESC_V6.5_UP_EARLY.V1_UP	3.18	EFNB2,DLC1,SASH1,EGLN3,KLF13,SUV39H2,HES6,SPOCK2,DACH1,NARF,PRICKLE1,SLC29A4,CGNL1,MAGI3
onco_sig_ERB2_UP.V1_UP	3.17	EDN1,PTGER4,DAB2,ABCC3,EPAS1,DRAM1,KMO,EGLN3,LIMCH1,CAMK2N1,TPK1,VTCN1,AKR1C2,VIPR1,HOXB7
onco_sig_ATF2_UP.V1_UP	3.15	MMP1,PLAU,TK1,TRPM2,KCNK3,PODXL,NEDD9,HOXD1,DTL,ABLIM3,GDF10,FOXM1,NCAPG,RAD51,CENPO
onco_sig_IL2_UP.V1_UP	3.15	FOS,EGR3,CXCL12,SLC7A5,RGS16,MAFF,PUS1,CDC25A,CD69,HEG1,KCNK5,STX11,TPBG,KIF1C,EHD2
onco_sig_NRL_DN.V1_DN	3.09	ADRB2,SOCS3,JAM3,LMNB2,NR4A1,CDT1,DIXDC1,ADRB1,ABCC9,PLEKHH2,ALDH2,MAP6
onco_sig_ERB2_UP.V1_DN	3.04	EGR3,GFRA1,DLC1,CAV1,FHL2,MYBL1,DBF4,DTL,PUS1,DEPDC1,MAD2L1,TTK,NCAPG,RAD51AP1,RAD54B
onco_sig_SRC_UP.V1_DN	2.98	IL7R,MMP1,E2F8,PTGER4,EZH2,PKP2,SUV39H2,FRMD4B,GINS1,MCM4,ATAD2,UHRF1,CENPH,RACGAP1
onco_sig_TBK1.DF_UP	2.91	HBEGF,PLAU,CXCL2,PID1,DAB2,VCAN,TNS3,MYBL1,CYBRD1,SIRPA,STEAP1,SPOCK1,STX12,GINS1,ADCY9,AVL9,RAD51AP1,NETO2,DNMT3B
onco_sig_KRAS.KIDNEY_UP.V1_DN	2.89	THBD,IL6,FOXA1,CNN1,RASGRF1,ITIH5,ACE,SEMA5A,THRB,TCF21,STX11,ABCA3
onco_sig_PDGF_UP.V1_UP	2.8	FOS,EGR3,SLC7A5,KCNK3,CCNE1,NCKAP1L,NEDD9,CDC25A,CDC6,DIXDC1,ARHGEF15,CBX2
onco_sig_JNK_DN.V1_DN	2.73	RGS16,ANKRD1,NELL2,CDC45,ACVRL1,ABCA4,SVEP1,UBE2C,STEAP1,IRF8,NDRG2,NPR1,CDKN3,NRGN
onco_sig_TGFB_UP.V1_DN	2.71	THBD,PTGER4,CXCL2,TEK,SDPR,ADRB2,MYBL1,ADAMTS1,RASGRF1,FRMD4B,SKP2,KIF18A,MITF,SEPT4
onco_sig_RAF_UP.V1_UP	2.64	HBEGF,PTGER4,ABCC3,NR4A3,EPAS1,JAM2,CAMK2N1,HEG1,TSPAN12,RCAN1,VTCN1,FAM49A,KAT2B,CABYR
onco_sig_KRAS.600_UP.V1_UP	2.61	HBEGF,ITGA2,MMP1,PLAU,STX1A,NTM,KCNK3,NR4A3,ETV1,CMKLR1,PDE2A,LIMCH1,ARHGAP24,FLT4,LRCH1,ZEB1,MAPK10,TLR8
onco_sig_CTIP_DN.V1_DN	2.45	EDN1,TSPAN7,CMKLR1,CYBRD1,MAOB,RASGRF1,CX3CL1,ECE2,PTGIR,LRRC32,ABI3BP
onco_sig_JAK2_DN.V1_UP	2.38	NELL2,DMD,KLF13,HOXD1,SUV39H2,COL6A3,JAM2,AFF3,SEMA5A,ZEB1,AGTR2,SPN,CDH5
onco_sig_KRAS.LUNG.BREAST_UP.V1_DN	2.36	ANKRD1,COL5A2,TRPM2,KRT4,DPT,MXD3,CD36,METTL7A,SCN7A,SOBP,RARRES2
onco_sig_ALK_DN.V1_DN	2.3	FOS,CMKLR1,DIO2,FOXA1,NDRG2,FXYD6,SLA,C16orf59,THSD4,CNTNAP2,KIAA0408
onco_sig_AKT_UP.V1_UP	2.26	EDN1,AK4,UBE2C,SLC2A1,KCNK5,HN1,CXCL16,TRAF4,TFRC,RHOV,GPX8,AKAP2
onco_sig_CSR_EARLY_UP.V1_DN	2.18	GFRA1,SDPR,PDE5A,HOXA10,SULF1,SKP2,COL1A1,LRRK2,ARRDC4,OTUD1,ALDH1L2
onco_sig_KRAS.600_UP.V1_DN	2.15	EDN1,THBD,ANKRD1,RRAD,TRPM2,KRT4,DPT,MXD3,TGFB2,CD36,ZBTB16,SYNPO,THRB,DBF4B,SCN7A,HLA-DOA,VGLL3
onco_sig_KRAS.600.LUNG.BREAST_UP.V1_UP	2.15	HBEGF,ITGA2,MMP1,STX1A,CXCL2,NTM,NELL2,CMKLR1,PDE2A,HOXD1,PPP1R15A,ARHGAP24,CD37,FLT4,DNAH9,SLIT2,MAPK10
onco_sig_TGFB_UP.V1_UP	2.1	EDN1,KLF4,RRAD,DLC1,CTGF,JAM2,FLT4,BMPR2,FOXF2,FAT4,NFATC4,NDST1,UBL3
onco_sig_PRC2_EDD_UP.V1_DN	2.08	CCND2,DMD,PLSCR4,ARHGAP24,SLC12A8,C1orf21,IRF8,RASL12,DKK2,AVL9,SEMA6D,NR3C2,MAPK8IP3
onco_sig_HOXA9_DN.V1_UP	2.08	FOS,KLF4,THBD,PTGER4,GAS7,VCAN,NCF2,COL6A3,STX12,TPK1,FRY,SESN1,CHPF2
onco_sig_MTOR_UP.N4.V1_UP	2.07	IL7R,SLC7A5,SLC7A11,ASNS,ELOVL6,ADARB1,SYNPO,OGN,PYCR1,MFAP4,PHACTR2,DNMT3B,RBM28
onco_sig_PTEN_DN.V2_UP	1.97	IL7R,PLAU,LOXL2,SPOCK1,GPM6A,CHRDL1,TBX5,AGPAT4,HSPB7,UTRN
onco_sig_EIF4E_DN	1.97	PLAU,GATA6,TPD52,FRMD4B,LMO7,FZD3,NEDD4L,ITPRIP
onco_sig_CAHOY_ASTROCYTIC	1.97	SLC7A11,ASNS,DIO2,CHRDL1,AGPAT4,TTYH3,ATP13A4,IL17RD
onco_sig_BMI1_DN.V1_DN	1.96	FOS,PID1,GAS7,GPX3,ETV1,PDE5A,METTL7A,MAOB,NDRG2,SFXN1
onco_sig_P53_DN.V2_DN	1.94	ALOX5,BMPR2,C1orf21,SSTR1,HMMR,RAB8B,RECK,CCNF,E2F2,CENPA
onco_sig_KRAS.BREAST_UP.V1_DN	1.94	ANKRD1,COL5A2,DPT,SELENBP1,SCN7A,SOBP,NPR1,TSPAN12,IL18R1,NFATC4
onco_sig_KRAS.LUNG.BREAST_UP.V1_UP	1.94	HBEGF,ITGA2,MMP1,CXCL2,NTM,NELL2,CMKLR1,PDE2A,CD37,DNAH9
onco_sig_GCNP_SHH_UP_LATE.V1_DN	1.92	EDN1,PTGER4,STX1A,ADRB2,KANK3,PUS1,CNN1,SLC2A1,CX3CL1,ADCY9,ATAD3A,LYSMD1
onco_sig_KRAS.BREAST_UP.V1_UP	1.92	STX1A,CXCL2,KCNK3,CMKLR1,PDE2A,PPP1R15A,FMO2,MAPK4,TLR8,CASS4
onco_sig_STK33_DN	1.88	RGS16,APBB2,ASNS,ELOVL6,PODXL,LAMP3,ALOX5,HOXA10,AFF3,HES6,GPM6A,CAD,C4orf32,LRRK2,GPM6B,STX11
onco_sig_RB_DN.V1_DN	1.88	SLC7A5,ADAM12,CAV1,IL33,NEDD9,ADAMTS1,RHOV,FHL1,MYADM
onco_sig_ATM_DN.V1_DN	1.87	TEK,ACVRL1,CD69,BMPR2,DNAH9,RAPGEF4,CYBB,NTRK2,RDX,MS4A2
onco_sig_CYCLIN_D1_UP.V1_UP	1.86	KLF4,THBD,FHL2,PDE2A,KCNAB2,SPOCK2,RASGRF1,PTPN21,CHRNA5,SLC12A4,SGCA,MKI67
onco_sig_NOTCH_DN.V1_DN	1.85	IL7R,DRAM1,DIO2,TUBB2B,ZBTB16,RPL39L,CD27,WIF1,E2F2,ACADL,FIGF,ARHGAP6
onco_sig_HINATA_NFKB_IMMU_INF	1.76	CXCL2,OLR1,IL6
onco_sig_WNT_UP.V1_DN	1.73	THBD,EFNB2,ADAM12,ABCC3,GPX3,DIO2,TGFBR3,MET,PCDH7,ADRB1,CD93
onco_sig_STK33_NOMO_DN	1.68	APBB2,ASNS,LAMP3,EGLN3,ALOX5,HOXA10,AFF3,HES6,GPM6A,SOBP,C4orf32,LRRK2,CHRDL1,STX11,IL18R1,BTBD11
onco_sig_RB_P130_DN.V1_DN	1.64	CXCL12,OLR1,ARHGAP24,SLC2A1,RAB8B,ARRDC4,RHOV,ABCG2,AVL9
onco_sig_CRX_NRL_DN.V1_UP	1.63	GAS7,WISP1,MEST,BUB1B,FXYD6,AQP1,RNF207,RHPN1,CTIF
onco_sig_RAPA_EARLY_UP.V1_UP	1.62	COL5A2,PDE2A,PDE5A,KIAA0040,SYNPO,PTPRD,PTGIR,HSPB6,ARHGEF15,FGFR2,PIP5K1B
onco_sig_AKT_UP_MTOR_DN.V1_UP	1.61	EDN1,HBEGF,EFNB2,SLC39A8,DUSP1,AK4,KCNK5,ARRDC4,CXCL16,GPX8,AKAP2
onco_sig_ESC_J1_UP_LATE.V1_DN	1.59	EDN1,KLF4,E2F8,DLC1,SOCS3,TUBB2B,JAM2,LMNB2,POLE,TUBB3,ACACB
onco_sig_IL21_UP.V1_DN	1.58	ITGA2,TSPAN7,MYLK,CMKLR1,LMOD1,HKDC1,LRCH1,SCN7A,KIAA1462,MEOX2,FRMD4A
onco_sig_IL15_UP.V1_DN	1.54	ADAM12,MYLK,TNS3,PLCL1,RASL12,KIAA1462,SESN1,SEMA6D,SELP,MMP19,PIK3IP1
onco_sig_SIRNA_EIF4GI_DN	1.54	LOXL2,CDC6,PSMC3IP,TRIP13,CFTR,SRPK1,MYO19
onco_sig_RAPA_EARLY_UP.V1_DN	1.53	TRPM2,KRT4,NCAPH,AXL,CRY2,FAM49A,PRKCE,MET,AOC3,PLEKHO2,PRELP
onco_sig_JNK_DN.V1_UP	1.52	RRAD,ADAM12,TEK,CD37,TBX2,RUNX2,RASSF2,ACADL,SYNE1,STARD13,CLDN18
onco_sig_CAHOY_ASTROGLIAL	1.52	LOXL2,PKP2,CNN1,OGN,PSRC1,PCDH17,ATOH8
onco_sig_MTOR_UP.N4.V1_DN	1.51	BTG2,CCNE1,CBFA2T3,ZBTB16,CAMK2N1,PLCL1,CBX7,DACH1,KAT2B,EVI2B,SPATS2
onco_sig_IL21_UP.V1_UP	1.51	CXCL12,SLC7A5,LAMP3,SLC12A8,HEG1,ABCA6,CDH5,FOSB,TPBG,FAM107A,SPARCL1
onco_sig_STK33_SKM_DN	1.5	RGS16,APBB2,ASNS,ELOVL6,PODXL,TPD52,ALOX5,AFF3,C4orf32,LRRK2,GPM6B,CXCL16,SV2A,ALDH1L2,N4BP2L1
onco_sig_KRAS.DF.V1_DN	1.5	KLF4,LCP1,ADRB2,LAMP3,SIRPA,ALOX5,UCHL1,TNXB,HSPB6,SYNE1,SEMA6A
onco_sig_VEGF_A_UP.V1_UP	1.48	NCF2,ABCA4,LMOD1,ADARB1,KANK3,NEDD9,MYO1F,SEMA5A,KIAA1462,ZCCHC24,ITM2A
onco_sig_LTE2_UP.V1_DN	1.48	EGR3,KLF4,SLC7A11,GFRA1,DLC1,CAV1,EFEMP1,CBFA2T3,FHL2,LAMP3,EPB41L2
onco_sig_BRCA1_DN.V1_UP	1.41	CMKLR1,CD34,HOXB7,SGCA,THBS2,LDB2,RCN3,CILP,CYP2U1
onco_sig_KRAS.LUNG_UP.V1_UP	1.41	HBEGF,ITGA2,MMP1,NTM,NELL2,SLC6A4,CX3CR1,PCDH17,C17orf53
onco_sig_KRAS.PROSTATE_UP.V1_DN	1.39	EDN1,RRAD,KRT4,ZBTB16,MAOB,CRY2,SLC19A3,VGLL3,SH2D3C
onco_sig_WNT_UP.V1_UP	1.35	FOS,AURKB,OLR1,IL6,THRB,TPK1,CDH5,TEF,HTRA3,COL4A4
onco_sig_PDGF_ERK_DN.V1_DN	1.35	IL7R,EFNB2,DUSP1,MAFF,TBX2,CKS2,EFNA3,CCNF,MAP3K3
onco_sig_GLI1_UP.V1_UP	1.3	CCND2,ZBTB16,LMO7
onco_sig_CAMP_UP.V1_UP	1.28	FOS,KIAA0040,PPP1R15A,SELENBP1,COL6A3,NDRG2,MAD2L1,ZNF367,MTHFD2,SRPK1,CHAF1A
onco_sig_BCAT_GDS748_UP	1.25	NEDD9,PKP2,LMO2,FLT4
onco_sig_KRAS.50_UP.V1_DN	1.22	RRAD,TRPM2,KRT4,THRB
onco_sig_NRL_DN.V1_UP	1.18	GAS7,WISP1,AQP1,RNF207,RHPN1,NUF2,CTIF,CCNA2
onco_sig_RELA_DN.V1_DN	1.15	IL7R,C1orf21,KCNK5,TBX5,TEF,DNMT3A,C7,CASC5
onco_sig_PDGF_UP.V1_DN	1.14	IL7R,ACVRL1,HOXD1,TBX2,ACADL,LIMK1,MXRA5,CDC14A
onco_sig_CAHOY_OLIGODENDROCUTIC	1.12	ELOVL6,CTGF,SEMA5A,LHFP,PLLP,CNTNAP2
onco_sig_CYCLIN_D1_KE_.V1_UP	1.11	EGR3,KLF4,THBD,COL5A2,ASNS,FHL2,KCNAB2,CHRNA5,PPM1F,TGFBR2
onco_sig_PRC2_SUZ12_UP.V1_DN	1.11	EDN1,HBEGF,ITGA2,LCP1,ACE,CBX7,C1orf21,DACH1,PTGIR,MTMR10
onco_sig_PRC1_BMI_UP.V1_DN	1.1	EDN1,RGS16,NTM,TSPAN7,CCND2,DMD,ACE,IRF8,DKK2,HSPB7
onco_sig_KRAS.AMP.LUNG_UP.V1_DN	1.1	MXD3,CRY2,ACE,DBF4B,GDF10,BARX2,CD34,SLC19A3
onco_sig_KRAS.300_UP.V1_UP	1.1	ITGA2,MMP1,NTM,ETV1,PDE2A,ARHGAP24,LRCH1,MAPK10
onco_sig_PIGF_UP.V1_DN	1.09	NELL2,CBFA2T3,AK4,SVEP1,MYO1F,KCNAB2,CDC20,ADH1B,SPN,NFASC
onco_sig_BMI1_DN_MEL18_DN.V1_DN	1.09	FOS,GAS7,GPX3,PDE5A,ABCA4,METTL7A,MAOB,MXRA5
onco_sig_KRAS.600.LUNG.BREAST_UP.V1_DN	0.96	ANKRD1,COL5A2,TRPM2,KRT4,DPT,MXD3,CD36,METTL7A,SELENBP1,SCN7A,SOBP,IL18R1,RARRES2
onco_sig_CRX_NRL_DN.V1_DN	0.96	ADRB2,JAM3,NR4A1,NTN4,RTKN2,ABCC9,RERG
onco_sig_ESC_V6.5_UP_LATE.V1_DN	0.92	KLF4,E2F8,SOCS3,JAM2,CBX7,TUBB3,KAT2B,KIF18A,ACACB
onco_sig_PIGF_UP.V1_UP	0.89	ITGA2,VCAN,KIAA0040,SULF1,TGFBR3,ABCA8,MMRN1,PPAT,CPD
onco_sig_NOTCH_DN.V1_UP	0.87	RRAD,BTG2,SDPR,DPT,ADAMTS1,BARX2,EFNA3,RUNX2,TNS1
onco_sig_PKCA_DN.V1_UP	0.79	EGR3,IL33,CD36,TUBB2B,PSMC3IP,TSKU,TEF,FBLN1
onco_sig_BCAT_GDS748_DN	0.79	MYBL1,SKP2,CDK5RAP3
onco_sig_KRAS.50_UP.V1_UP	0.77	ITGA2,NTM,ETV1
onco_sig_BCAT.100_UP.V1_UP	0.75	DKK1,EFEMP1,LMO2
onco_sig_BCAT_BILD_ET_AL_UP	0.75	SIRPA,DACH1,MYADM
onco_sig_TBK1.DN.48HRS_DN	0.74	STX1A,CDK1,BIRC5
onco_sig_PTEN_DN.V2_DN	0.69	MXD3,STMN1,CBX7,RECQL4,REPS2,FANCA,BARX2
onco_sig_KRAS.300_UP.V1_DN	0.69	RRAD,TRPM2,KRT4,DPT,MXD3,SYNPO,THRB
onco_sig_PDGF_ERK_DN.V1_UP	0.68	NCKAP1L,ACP5,STX12,COL1A1,CHEK2,TBX5,FLI1
onco_sig_CSR_EARLY_UP.V1_UP	0.61	HBEGF,KLF13,TBX2,REPS2,DKC1,C8orf76,HMGA1
onco_sig_MYC_UP.V1_DN	0.59	MMP1,IL6,GINS1,HEG1,PSMC3IP,CDCA8,GPRC5A,PDZD2
onco_sig_E2F3_UP.V1_DN	0.58	MMP1,THBD,STX1A,IL6,NCKAP1L,GPRC5A,FBXL19,CBX3
onco_sig_PTEN_DN.V1_DN	0.57	TSPAN7,LCP1,HMGCS1,GPM6A,ABCA6,NR3C2,TPPP3,HEYL
onco_sig_DCA_UP.V1_UP	0.56	ANKRD1,AURKB,CDC45,WISP1,ACP5,CD27,LIMD1,MYCT1
onco_sig_BRCA1_DN.V1_DN	0.5	WFDC1,NRGN,E2F2,EPB41L5,MEOX2,BRCA1
onco_sig_KRAS.LUNG_UP.V1_DN	0.5	KRT4,METTL7A,ERG,FMO2,SGCD,ATAT1
onco_sig_ATM_DN.V1_UP	0.49	SLC7A5,CD36,ADARB1,RECQL4,ABCA8,CLIC5
onco_sig_ESC_J1_UP_EARLY.V1_DN	0.44	EDN1,KLF4,SOCS3,KLF13,ZFP36,CNN1,EMP2
onco_sig_BCAT.100_UP.V1_DN	0.42	TBX5,FZD4
onco_sig_MEK_UP.V1_DN	0.29	EGR3,GFRA1,APBB2,DLC1,MYLK,ELOVL6,MYBL1
onco_sig_DCA_UP.V1_DN	0.29	CX3CL1,CHEK2,NR4A1,NFASC,ZCCHC24,CLIC5,ASPM
onco_sig_CAHOY_NEURONAL	0.27	STX1A,NRGN,RTN4RL1,PGM2L1
onco_sig_YAP1_DN	0.19	ITGA2,LIMD1
onco_sig_MYC_UP.V1_UP	0.18	FOS,PUS1,ECE2,METTL1,SLC29A4,HLF
onco_sig_PRC1_BMI_UP.V1_UP	0.18	LMOD1,HOXA10,CLSPN,TSPAN12,CACNA2D2,PEAK1
onco_sig_SIRNA_EIF4GI_UP	0.12	BTG2,NCAPD2,HSPD1
onco_sig_CTIP_DN.V1_UP	0.1	TEK,GDF10,CD34,GNG7
onco_sig_CRX_DN.V1_DN	0.1	SOCS3,JAM3,PYCR1,C1QTNF6
onco_sig_RB_P107_DN.V1_DN	0.1	EDN1,CXCL12,ELOVL6,ACP5
onco_sig_SRC_UP.V1_UP	0.08	FOS,LAMP3,IRF8,COL4A4
onco_sig_KRAS.AMP.LUNG_UP.V1_UP	0	NELL2,SSTR1,EFNA3,SOX12
onco_sig_JAK2_DN.V1_DN	0	MYBL1,DBF4B,SLC15A2,GABRE
onco_sig_EIF4E_UP	0	METTL1,NEGR1